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Vinylogous acids

Organic compounds that contain one or more hydroxyl groups indirectly attached to a carbonyl group via an intervening vinyl functional group (-C=C-; also known as carbon - carbon double bond).
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Keyword Search:
271 – 285 of 385 results
271

eMolecules​ 74711-43-6 | 2-(10,11-Dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic Acid | Combi-Blocks | MFCD00864323 | 298.360 | C17H14O3S | 98.000 | CC(C(O)=O)c1ccc2Sc3ccccc3C(=O)Cc2c1 | 1g | 232332897

2-(10,11-Dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic Acid | Combi-Blocks | 74711-43-6 | MFCD00864323 | 298.360 | C17H14O3S | 98.000 | CC(C(O)=O)c1ccc2Sc3ccccc3C(=O)Cc2c1 | 1g | 232332897

ENCOMPASS_PREFERRED
272

eMolecules​ 1001-26-9 | Ethyl 3-ethoxyprop-2-enoate | Combi-Blocks144.170 | C7H12O3 | 95.000 | CCOC=CC(=O)OCC | 25g | 205384295

Ethyl 3-ethoxyprop-2-enoate | Combi-Blocks | 1001-26-9144.170 | C7H12O3 | 95.000 | CCOC=CC(=O)OCC | 25g | 205384295

ENCOMPASS_PREFERRED
273

Medchemexpress LLC 6,7-dimethoxy-4-[(3R)-3-(2-quinoxalinyloxy)-1-pyrrolidinyl]-quinazoline | 927691-21-2 | MFCD12828216 | >98.0% | 403.43 | C22H21N5O3 | 10 MG
SDP

PQ-10 (6,7-dimethoxy-4-[(3R)-3-(2-quinoxalinyloxy)-1-pyrrolidinyl]-quinazoline) is a selective phosphodiesterase 10A (PDE10A) inhibitor provided as a research reagent. It demonstrates low-nanomolar in vitro potency and has been used in preclinical studies to probe PDE10A-related signaling and brain glucose metabolism. For research use only; not for human or clinical use.

  • Selective PDE10A inhibitor with low-nanomolar potency.
  • Reported in vivo activity supporting preclinical studies.
  • Chemical identity: C22H21N5O3, molecular weight 403.43.
  • Supplied in small research quantities (example: 10 mg).
  • For research use only; not intended for human use.

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274

Frontier Specialty Chemicals 1G 1-METHYL-5-(TRIFLUOROMETHYL

1-Methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; CAS: 119083-00-0; 1g

ENCOMPASS_PREFERRED
275

Frontier Specialty Chemicals 5G 1-METHYL-5-(TRIFLUOROMETHYL

1-Methyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid; CAS: 119083-00-0; 5g

ENCOMPASS_PREFERRED
276

Medchemexpress LLC Boc-val-cit-pab-pnp | 870487-10-8 | 99.6% | 644.67 | C30H40N6O10 | 50 MG
SDP

Boc-Val-Cit-PAB-PNP is a protease-cleavable linker used to construct antibody-drug conjugates (ADCs). It releases payloads after intracellular proteolytic cleavage and is supplied as a solid with high purity.

  • Cleavable val-cit peptide linker releasing payload upon proteolysis
  • Para-aminobenzyl spacer with p-nitrophenyl leaving group
  • High purity suitable for research applications
  • Soluble in DMSO at 100 mg/mL with ultrasonic assistance
  • Recommended storage: -20°C under nitrogen; in solvent store at -80°C for long-term
  • Available in small research scales, e.g. 50 mg

ENCOMPASS_PREFERRED
277

eMolecules​ 1306748-36-6 | trans-5-Boc-amino-cyclohex-3-enecarboxylic acid ethyl ester | J & W PharmLab LLC538.682 | C28H46N2O8 | 97.000 | CCOC(=O)[C@H]1CC=C[C@@H](C1)NC(=O)OC(C)(C)C.CCOC(=O)[C@@H]1CC=C[C@H](C1)NC(=O)OC(C)(C)C | 1g | 525341606

trans-5-Boc-amino-cyclohex-3-enecarboxylic acid ethyl ester | J & W PharmLab LLC | 1306748-36-6538.682 | C28H46N2O8 | 97.000 | CCOC(=O)[C@H]1CC=C[C@@H](C1)NC(=O)OC(C)(C)C.CCOC(=O)[C@@H]1CC=C[C@H](C1)NC(=O)OC(C)(C)C | 1g | 525341606

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278

Medchemexpress LLC Ensitrelvir fumarate | 2757470-18-9 | 100.0% | C26H21ClF3N9O6 | 50 MG
SDP

Ensitrelvir fumarate, also known as S-217622 fumarate, is the first orally active, non-covalent, and non-peptidic SARS-CoV-2 3CL protease inhibitor with an IC50 of 13 nM. It demonstrates significant antiviral activity against various SARS-CoV-2 variants, SARS-CoV, and MERS-CoV.

  • First orally active, non-covalent, non-peptidic SARS-CoV-2 3CL protease inhibitor
  • Inhibits SARS-CoV-2 3CL protease with an IC50 of 13 nM
  • Effective against wild-type SARS-CoV-2 and Alpha, Beta, Gamma, and Delta variants with EC50 values around 0.4 μM
  • Shows EC50 values of 0.21 μM for SARS-CoV and 1.4 μM for MERS-CoV
  • Dose-dependently inhibits intrapulmonary replication of SARS-CoV-2 in mice

ENCOMPASS_PREFERRED
279

Medchemexpress LLC Adenylosuccinic acid tetraammonium | >98% | 10 MG
SDP

Adenylosuccinic acid tetraammonium is an orally active purine ribonucleoside monophosphate involved in nucleotide cycle metabolism. This compound can be converted into fumaric acid via adenylosuccinate lyase and holds potential for the study of Duchenne muscular dystrophy (DMD).

  • Orally active purine ribonucleoside monophosphate
  • Plays a role in nucleotide cycle metabolism
  • Converts into fumaric acid via adenylosuccinate lyase
  • Potential for Duchenne muscular dystrophy (DMD) research
  • Ameliorates murine Duchenne muscular dystrophy symptoms in vivo

ENCOMPASS_PREFERRED
280

eMolecules​ 837392-64-0 | 2-Oxoindoline-5-boronic Acid Pinacol Ester | MFCD08669935 | 1g

Ambeed | 2-Oxoindoline-5-boronic Acid Pinacol Ester | 1g | 527374796 | A463807 | 837392-64-0 | MFCD08669935 | 259.110 | C14H18BNO3

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281

eMolecules​ 87-13-8 | Ethyl ethoxymethylene malonate | Oakwood Chemical | MFCD00009148 | 216.233 | C10H16O5 | 98.000 | CCOC=C(C(=O)OCC)C(=O)OCC | 500g | 537687906

Ethyl ethoxymethylene malonate | Oakwood Chemical | 87-13-8 | MFCD00009148 | 216.233 | C10H16O5 | 98.000 | CCOC=C(C(=O)OCC)C(=O)OCC | 500g | 537687906

ENCOMPASS_PREFERRED
282

Sigma Aldrich Fine Chemicals Biosciences Hypoxanthine >=99.0% | 68-94-0 | MFCD00005725 | 25G

Hypoxanthine >=99.0% | Purity: >=99.0% | Mol Wt: 136.11 | 68-94-0 | MFCD00005725 | 25G

ENCOMPASS
283

eMolecules​ 1670-97-9 | N-COOCH3-Gly-OH | Ambeed | MFCD00270561 | 133.103 | C4H7NO4 | 97.000 | COC(=O)NCC(O)=O | 250mg | 525029727

N-COOCH3-Gly-OH | Ambeed | 1670-97-9 | MFCD00270561 | 133.103 | C4H7NO4 | 97.000 | COC(=O)NCC(O)=O | 250mg | 525029727

ENCOMPASS_PREFERRED
284

Sigma Aldrich Fine Chemicals Biosciences Hypoxanthine powder, BioReagent, suitable for cell culture | 68-94-0 | MFCD00005725 | 5G

Hypoxanthine powder, BioReagent, suitable for cell culture | Purity: >=99% | Mol Wt: 136.11 | 68-94-0 | MFCD00005725 | 5G

ENCOMPASS
285

eMolecules​ 143688-82-8 | 10-(Fmoc-amino)decanoic acid | Acrotein ChemBio Inc. | MFCD00270352 | 409.526 | C25H31NO4 | 97 | OC(=O)CCCCCCCCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 518512956

Pharmablock | 2-bromopropanenitrile | 25mg | 716243902 | PBT6019 | 19481-82-4 | MFCD00010383 | 133.976 | C3H4BrN

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